Yep, Higgins will play more forward (replacing Bolton) with George and Rioli. You don't really need an old school CHF at Etihad so with Jack & Moore as the tall targets, Caddy will be able to spend more time in the midfield rotation. Alternatively, Moore and Caddy play deep leading out from the square while Jack plays high.
Brandon will move from defence into the midfield rotation (replacing Corey Ellis) with Broad back. McIntosh and/or Menadue to sweep off HB and the wings effectively replacing Houli. So all up our basic team structure will remain the same despite a change and rotation in personnel.