Author Topic: Depressing news for drug companies!  (Read 3881 times)

Moi

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Depressing news for drug companies!
« on: February 27, 2008, 08:13:07 AM »
Claims their drugs don't work.  Research based on the drug companies' own data lol
Now, I'm not saying to people to give away their medications, but a little discussion with their doctors if you are taking them might be in order :-)

What this makes me ask is what other medications might people be taking that drug companies data shows little difference between the drug and the placebo.

http://afp.google.com/article/ALeqM5idJMA3ijPV9hXfLkfw0p-Y5qvE2A


Depression drugs 'little better than placebos': study
5 hours ago

LONDON (AFP) — Best-selling anti-depressants like Prozac and Seroxat are barely more effective than placebos in treating most people with depression, a study led by a British university said Tuesday.

The research, which analysed 47 clinical trials, breaks new ground by incorporating data not previously released by drug companies which researchers obtained under US freedom of information laws.

Its findings prompted some academics and mental health campaigners to question whether people with mild and moderate depression should be prescribed drugs like Prozac, which has been taken by 40 million people worldwide.

"The difference in improvement between patients taking placebos and patients taking anti-depressants is not very great," said Professor Irving Kirsch of Hull University, in northern England, who led the team.

"This means that depressed people can improve without chemical treatments.

"Given these results, there seems little reason to prescribe antidepressant medication to any but the most severely depressed patients unless alternative treatments have failed to provide a benefit."

The study, published in the journal PLoS (Public Library of Science) Medicine, looked at Prozac, Seroxat, Effexor and Serzone and found the drugs were only better than a placebo for some people with severe depression.

Kirsch's team said it was one of the most thorough probes into the impact of new generation anti-depressants or selective serotonin reuptake inhibitors (SSRIs).

But drug companies strongly questioned the findings.

A spokesman for Eli Lilly, which makes Prozac, said that "extensive scientific and medical experience" had shown it is "an effective anti-depressant."

And GlaxoSmithKline, which makes Seroxat, said the study had not acknowledged the "very positive benefits" of the drugs.

"Their conclusions are at odds with what has been seen in actual clinical practice," a spokesman said.

"It is widely recognised by experts in the field that studies in depression are challenging and very difficult to conduct."

One leading academic who has studied why drug companies only publish some of their data on new drugs said in the wake of the findings they should be obliged to provide full details.

Doctor Tim Kendall, deputy director of Britain's Royal College of Psychiatrists research unit, said the study was "fantastically important."

"I think it's too dangerous to allow drug companies -- where profit is a key factor -- to be able to withhold data which shows that a drug is ineffective or harmful," he said.

Alison Cobb, of British mental health charity Mind, hailed the findings as "a serious challenge to the predominance of drugs in treating depression."

"Anti-depressants do help many people but by no means all and some people experience severe side-effects with them," she said.

"Nine out of 10 GPs (general practitioners) say they've been forced to dish out drugs because they don't have proper access to 'talking treatments' such as cognitive behavioural therapy, which are recommended as the first-line treatment for mild to moderate depression."

Another mental health charity, Sane, warned the findings "could remove what has been seen as a vital choice for thousands," adding people should not stop taking their drugs immediately.

As the study was published, the British government published details of a 170-million-pound (225-million-euro, 335-million dollar) programme to improve access to counselling and therapy for people with depression.

Officials say this should see 900,000 more people receiving such treatments over the next three years.


Offline cub

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Re: Depressing news for drug companies!
« Reply #1 on: February 27, 2008, 09:02:20 AM »
A lot of people these days are whingeing sooks that need to get over themselves.
That's not to take serious depression lightly either.

Moi

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Re: Depressing news for drug companies!
« Reply #2 on: February 27, 2008, 09:12:19 AM »
A lot of people these days are whingeing sooks that need to get over themselves.
That's not to take serious depression lightly either.
Me neither.
Was looking more at the drug issue.
I wonder if the drug company executives took a Prozac when they read the report lol
I doubt it  :rollin

Ox

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Re: Depressing news for drug companies!
« Reply #3 on: February 27, 2008, 09:18:25 AM »
they all go home and smoke pot.

Moi

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Re: Depressing news for drug companies!
« Reply #4 on: February 27, 2008, 09:22:06 AM »
I guess it's a bit hard to bottle fresh air and exercise lol

Offline cub

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Re: Depressing news for drug companies!
« Reply #5 on: February 27, 2008, 09:39:03 AM »
Read somewhere recently that they can actually find traces of it in Londons drinking water.
They drink recycled water.
That tells me too many people think they have problems.
And if placebos have such a result then there you go .....

Soo much for the recycled water debate too - even tho all the water we drink is recycled in one way or another.
I think I will give this way a miss thankyou very much .....

Offline mightytiges

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Re: Depressing news for drug companies!
« Reply #6 on: February 27, 2008, 03:15:10 PM »
A pet hate - people with colds going to the doctor asking for antibiotics. I can understand if it's an infant or your elderly or you have respiratory problems but the majority of people aren't in those categories. Some doctors hand them out like their jelly beans too.
All you touch and all you see is all your life will ever be - Pink Floyd

Ox

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Re: Depressing news for drug companies!
« Reply #7 on: February 27, 2008, 03:45:05 PM »
I guess it's a bit hard to bottle fresh air and exercise lol

Wise words Moima.
but sometimes u need a line to be bothered to do either  :rollin